Stroke is a major cause of death and disability in industrialized countries. T...Stroke is a major cause of death and disability in industrialized countries. To date the medical need of efficient therapy for this de- vastating cerebrovascular disorder remains unmet. During the last decades the development of pharmacological...more
Inflammatory processes have been implicated in the pathophysiology of a variet...Inflammatory processes have been implicated in the pathophysiology of a variety of neurodegenerative diseases such as Alzheimer s disease stroke and mUltiple sclerosis. It is now widely accepted that the brain considered to be an immunologically...more
Inflammatory processes have been implicated in the pathophysiology of a variet...Inflammatory processes have been implicated in the pathophysiology of a variety of neurodegenerative diseases such as Alzheimer s disease stroke and mUltiple sclerosis. It is now widely accepted that the brain considered to be an immunologically...more
The European Workshops on Molecular and Cellular Endocrinology of the Testis h...The European Workshops on Molecular and Cellular Endocrinology of the Testis have become by now a well-established tradition. Thanks to their special format the quality of the main lectures and miniposters and the vivid discussions they enjoy the...more
Optimal dose individualization has become more important in improving clinical...Optimal dose individualization has become more important in improving clinical efficacy and safety given the variability in drug response e.g. due to concurrent illnesses or co-medications. Therefore the role of optimal dose finding in early...more
In recent years the importance of adjuvants for optimising the activity of agr...In recent years the importance of adjuvants for optimising the activity of agrochemicals has become increasingly recognized. This book is aimed at accumulating the current knowledge of the interactions between adjuvants agrochemicals and target...more
Health care delivery therapies and pharmaceuticals face major changes througho...Health care delivery therapies and pharmaceuticals face major changes throughout the industrial world. As cost containment strategies are introduced by governments as payers become more conscious and influential in their decisions about shaping...more
To mark the occasion of the lOOth anniversary of Schering research two events ...To mark the occasion of the lOOth anniversary of Schering research two events took place: a) a Workshop on Bioscience; =: Society which was held November 24-30 1990 in Berlin. The goal of the workshop was: Do current and anticipated developments in...more
What is a nongenotoxic carcinogen? This question recurred through- out the Ern...What is a nongenotoxic carcinogen? This question recurred through- out the Ernst Schering Research Foundation Workshop on nongeno- toxic carcinogenesis underlining the complexity of the topic. The clarity of the view that all carcinogens act by...more
Since 1948 hydrocortisone (cortisol) the principal glucocorticoid (GC) of the ...Since 1948 hydrocortisone (cortisol) the principal glucocorticoid (GC) of the human adrenal cortex has been successfully used at phar- macological concentrations for the suppression of clinical manifesta- tions of rheumatoid arthritis. Numerous...more
Alzheimer s Disease is a progressive neurodegenerative disorder of late life w...Alzheimer s Disease is a progressive neurodegenerative disorder of late life with devastating consequences for the afflicted and their carers and poses one of the major challenges to medical research. Until recently little hope of effective...more