High quality leads provide the foundation for the discovery of successful clin...High quality leads provide the foundation for the discovery of successful clinical development candidates and therefore the identi?cation of leads is an essential part of drug discovery. The process for the identi?cation of leads generally starts...more
MedicinalChemistryApproaches to Malaria and Other Tropical Disease Volume 53...Medicinal Chemistry Approaches to Malaria and Other Tropical Disease Volume 53 in the Annual Reports in Medicinal Chemistry series highlights new advances in the field with this new volume presenting interesting chapters. Each chapter is written by...more
Medicinal Natural Products: A Disease-Focused Approach Volume 55 in the Annual...Medicinal Natural Products: A Disease-Focused Approach Volume 55 in the Annual Reports in Medicinal Chemistry series highlights the applications of natural products as medicines or prospective medicinal leads for the treatment of various human...more
This volume provides an overview of neurodegenerative diseases. Topics include...This volume provides an overview of neurodegenerative diseases. Topics include the role histone deacetylases plays in neurodegenerative diseases phosphodiesterase inhibition as a way to target synaptic dysfunction in Alzheimer s disease and more.more
This volume provides an overview of neurodegenerative diseases. Topics include...This volume provides an overview of neurodegenerative diseases. Topics include the role histone deacetylases plays in neurodegenerative diseases phosphodiesterase inhibition as a way to target synaptic dysfunction in Alzheimer s disease and more.more
This book deals with the recent advances in DNA-Encoded Library (DEL) technolo...This book deals with the recent advances in DNA-Encoded Library (DEL) technology that has emerged as an alternative to high throughput screening (HTS) over the last decade and has been heralded as a disruptive technology for drug discovery. The book...more
Progress inMedicinalChemistry Volume 60 provides a review of eclectic develo...Progress in Medicinal Chemistry Volume 60 provides a review of eclectic developments in medicinal chemistry. Each chapter is written by an international board of authors who cover topics including Venoms in Drug Discovery Designing Protacs as a...more
Fully updated the third edition of this popular textbook remains comprehensive...Fully updated the third edition of this popular textbook remains comprehensive authoritative and readable. Taking a receptor-based target-centered approach it presents the concepts central to the study of drug action in a logical mechanistic way...more
New Approaches Towards Novel Antibacterial Agents Volume 60 in the Annual Repo...New Approaches Towards Novel Antibacterial Agents Volume 60 in the Annual Reports in Medicinal Chemistry series highlights new advances in the field with this new volume presenting interesting chapters written by an international board of authors.more
Some of the more recent efforts in tuberculosis (TB) and trypanosomiasis drug ...Some of the more recent efforts in tuberculosis (TB) and trypanosomiasis drug discovery from both Product Development Partnerships (PDPs) and academia are highlighted in this this volume. Drug discovery approaches include both target- and phenotypic...more
Fluorine chemistry is an expanding area of research that is attracting interna...Fluorine chemistry is an expanding area of research that is attracting international interest due to the impact of fluorine in drug discovery and in clinical and molecular imaging (e.g. PET MRI). Many researchers and academics are entering this area...more
MedicinalChemistry of Tick-Borne Encephalitis Volume 58 in the Annual Reports...Medicinal Chemistry of Tick-Borne Encephalitis Volume 58 in the Annual Reports in Medicinal Chemistry serial highlights new advances in the field with this new volume presenting interesting chapters on the Discovery of small molecule TBEV antivirals...more
Progress inMedicinalChemistry Volume 64 highlights new advances in the field...Progress in Medicinal Chemistry Volume 64 highlights new advances in the field with this new volume presenting interesting chapters written by an international board of authors.more
Progress inMedicinalChemistry provides a review of eclectic developments in ...Progress in Medicinal Chemistry provides a review of eclectic developments in medicinal chemistry. This volume includes chapters covering recent advances in cancer therapeutics fluorine in medicinal chemistry a perspective on the next generation of...more
Progress inMedicinalChemistry Volume 61 provides a review of eclectic develo...Progress in Medicinal Chemistry Volume 61 provides a review of eclectic developments in medicinal chemistry with each chapter written by an international board of authors.more