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Contemporary Neuroscience: Cor...The striatum is the principal input structure of the basal ganglia. Numericall... The striatum is the principal input structure of the basal ganglia. Numerically the great majority of neurons in the striatum are spiny projection neurons which produce the inhibitory output of the striatum to the globus pallidum and substantia... more
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Contemporary Hematology: Hemat...Here is a glimpse at the future of bone marrow derived stem cells in cardiac r... Here is a glimpse at the future of bone marrow derived stem cells in cardiac repair. The updated chapters in this second edition expound the biologic underpinnings of subjects including hematopoietic cell transplantation immunobiology and... more
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Handbook of Experimental Pharm...The aim of this textbook of molecular imaging is to provide an up to date revi... The aim of this textbook of molecular imaging is to provide an up to date review of this rapidly growing field and to discuss basic methodological aspects necessary for the interpretation of experimental and clinical results. Emphasis is placed on... more
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Contemporary Cardiology: Carot...In this book Jacqueline Saw and international experts on carotid artery stenti... In this book Jacqueline Saw and international experts on carotid artery stenting discuss in depth the details of all contemporary aspects of carotid stenting. They review supporting studies guidelines technical perspectives and peri-procedural... more
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Aspergillosis: From Diagnosis ...Aspergillosis is an infection or allergic response caused by the fungus Asperg... Aspergillosis is an infection or allergic response caused by the fungus Aspergillus. Aspergillus conidia are widely dispersed in the environment and can easily reach human lungs and/or paranasal sinuses: most people inhale Aspergillosis spores every... more
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Milestones in Drug Therapy: Er...This volume is a one-source guide to the most current information about red bl... This volume is a one-source guide to the most current information about red blood cell formation and the action of recombinant human erythropoietins. Topics in the fields of erythropoiesis recombinant protein discovery and production and treatment... more
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Methods of Cancer Diagnosis Th...Authors and Co-Authors of Volume 4 Preface Contents of Volume 1 2 and 3 PART I... Authors and Co-Authors of Volume 4 Preface Contents of Volume 1 2 and 3 PART I. COLORECTAL CANCER 1. INTRODUCTION: COLORECTAL CANCER M.A. Hayat INTRODUCTION Screening for Colorectal Cancer Treatment Rectal Cancer REFERENCES A. Diagnosis 2. POORLY... more
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Herbal Drugs: Ethnomedicine to...Considerable progress has been made in our healthcare system in particular wit... Considerable progress has been made in our healthcare system in particular with respect to sensitive diagnostic tools reagents and very effective and precise drugs. On the other hand high-throughput screening technology can screen vast numbers of... more
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Proteases in Biology and Disea...The 8th volume in the Proteases in Biology and Disease series focuses on the r... The 8th volume in the Proteases in Biology and Disease series focuses on the role of proteases in virus function and their potential as anti-viral targets. Viral infections are still difficult to threat and some remained life-threatening diseases in... more
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Pharmaceutical Perspectives of...The goal of our efforts in compiling Pharmaceutical Perspectives of Cancer The... The goal of our efforts in compiling Pharmaceutical Perspectives of Cancer Therapeutic is to produce a comprehensive yet easy-to-follow review of the principles and current approaches in this ever-growing field. With today s broad research... more
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Contemporary Neuroscience: New...Ischemic brain damage represents a major source of morbidity and mortality in ... Ischemic brain damage represents a major source of morbidity and mortality in westernized society and poses a significant financial burden on the health care system. To date few effective therapies have been realized. Recent evidence however... more
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Therapy of Skin Diseases: A Wo...Based on the understanding of the molecular basis of skin diseases this truly ... Based on the understanding of the molecular basis of skin diseases this truly international book supports the reader to understand the mode of action of new and established therapies. Thus by explaining the molecular pathology with its applications... more
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Cardiorenal Syndrome: Mechanis...Chronic kidney disease with a worldwide prevalence of 10% in the general popul... Chronic kidney disease with a worldwide prevalence of 10% in the general population is emerging as a major public health priority. Renal dysfunction is associated with a high risk for cardiovascular complications. The relationship between renal... more
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Contemporary Clinical Neurosci...Thiamine deficiency and related clinical disorders represent an intriguing are... Thiamine deficiency and related clinical disorders represent an intriguing area of both basic and clinical investigation. Modern imaging strategies have facilitated the rapid treatment and potential reversal of these clinical disorders. The fusion... more
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Cancer Genetics: Cancer Genome...Oncogenes and tumor suppressor genes had been traditionally studied in the con... Oncogenes and tumor suppressor genes had been traditionally studied in the context of cell proliferation differentiation senescence and survival four relatively cell-autonomous processes. Consequently in the late 80s-early 90s neoplastic growth was... more
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Advances in Experimental Medic...This volume contains the text of the presentations delivered at the Internatio... This volume contains the text of the presentations delivered at the International Symposium on Rare Diseases Inherited Neuromuscular Diseases: Translation from Pathomechanisms to Therapies held in Valencia Spain from November 16 to 18 2008. The... more
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Comparative Interpretation of ...Standard radiography of the chest remains one of the most widely used imaging ... Standard radiography of the chest remains one of the most widely used imaging modalities but it can be difficult to interpret. The possibility of producing cross-sectional reformatted 2D and 3D images with CT makes this technique an ideal tool for... more
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Cancer Treatment and Research:...Endocrine Neoplasia is a comprehensive updated and clearly-written text coveri... Endocrine Neoplasia is a comprehensive updated and clearly-written text covering the diseases for which endocrine surgical expertise is often needed. We look towards advances in the science and the art of endocrine surgery to continuously improve... more
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Hepatocellular Carcinoma: Targ...Hepatocellular Carcinoma: Targeted Therapy provides a detailed repository of t... Hepatocellular Carcinoma: Targeted Therapy provides a detailed repository of the latest information regarding HCC epidemiology diagnosis imaging pathology staging and treatment options. This volume also provides an up-to-date guide for treatment... more
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Handbook of Experimental Pharm...The world s population is growing at an unsustainable rate. From a baseline ?g... The world s population is growing at an unsustainable rate. From a baseline ?gure of one billion in 1800 global population is predicted to exceed nine billion by 2050 and 87. 8% of this growth will be localized in less developed countries. Such... more
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Allergy Frontiers: Allergy Fro...When I entered the field of allergy in the early 1970s the standard textbook w... When I entered the field of allergy in the early 1970s the standard textbook was a few hundred pages and the specialty was so compact that texts were often authored entirely by a single individual and were never larger than one volume. Compare this... more
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Beneficial Effects of Fish Oil...It is becoming increasingly evident that the deficiency of n-3 fatty acids in ... It is becoming increasingly evident that the deficiency of n-3 fatty acids in diet is not only associated with cardiovascular diseases but also involved in stroke epilepsy and other neurological and neurodegenerative diseases such as Alzheimer... more
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Contemporary Hematology: Manag...In this book the authors and editor draw on their extensive expertise to provi... In this book the authors and editor draw on their extensive expertise to provide a roadmap for hematologists to efficiently manage the complex infections within their patients. There are also extensive tables to allow for quick access to information. more
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Advances in Experimental Medic...Basic Science Underlying Retinal Degeneration.- Analysis of Genes Differential... Basic Science Underlying Retinal Degeneration.- Analysis of Genes Differentially Expressed During Retinal Degeneration in Three Mouse Models.- Regulation of Angiogenesis by Macrophages.- Protein Kinase C Regulates Rod Photoreceptor Differentiation... more
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Current Cancer Research: Prote...Protein kinase C (PKC) a family of serine-threonine kinases rocketed to the fo... Protein kinase C (PKC) a family of serine-threonine kinases rocketed to the forefront of the cancer research field in the early 1980 s with its identification as an effector of phorbol esters natural products with tumor promoting activity. Phorbol... more
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Current Clinical Oncology: Lun...Defining the Lung Cancer Problem 1 Lung cancer is the leading cause of cancer ... Defining the Lung Cancer Problem 1 Lung cancer is the leading cause of cancer death in the world. It kills almost as many Americans as cancers of the breast prostate colon rectum pancreas and 2 kidney combined and accounts for 28.6% of all US cancer... more
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Behçet s Syndrome (Hardcover)Behçet s Syndrome has seen great strides over the last two decades in the ava... Behçet s Syndrome has seen great strides over the last two decades in the availability of new treatments and the understanding of underlying pathogenesis. Only 30 years ago the majority of particularly young men with Behçet s lost total eye sight... more
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Contemporary Endocrinology: Am...This comprehensive book presents state-of-the-art and clinically-useful inform... This comprehensive book presents state-of-the-art and clinically-useful information on amenorrhea. Topics covered include causes diagnosis premature ovarian failure natural and surgical menopause and even the issue of ethnicity and amenorrhea. more
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Oxidative Stress in Applied Ba...Preface Contributor s List Chapters: 1) The evolving concept of oxidative stre... Preface Contributor s List Chapters: 1) The evolving concept of oxidative stress Denise de Castro Fernandes Diego Bonatto Francisco R. M. Laurindo 2) Mechanisms of redox signaling in cardiovascular disease Rebecca L. Charles Joseph R. Burgoyne and... more
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Contemporary Hematology: Adult...Adult Acute Lymphocytic Leukemia: Biology and Treatment Adult Acute Lymphocytic Leukemia: Biology and Treatment more
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Cancer Metastasis - Biology an...Colorectal cancer is the third most common cancer worldwide and in many parts ... Colorectal cancer is the third most common cancer worldwide and in many parts of the western world it is the second leading cause of cancer-related deaths. This book covers colon cancer metastasis from the most fundamental aspects to clinical... more
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Laron Syndrome - From Man to M...First book covering this interesting topic written by Zvi Laron who first desc... First book covering this interesting topic written by Zvi Laron who first described and reported the condition in 1966 (this syndrome is named after him) Describes the comprehensive pathophysiology of IGF-I deficiency and gives valuable advice for... more
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Current Clinical Oncology: Mye...Multiple myeloma is the second most common hematologic malignancy and c- rentl... Multiple myeloma is the second most common hematologic malignancy and c- rently affects approximately 50 000 people in the United States. Each year about 20 000 people are diagnosed with myeloma. Although new treatments have been developed which... more
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Current Clinical Urology: Kidn...This practical guide is grounded in tested clinical practices and overall clin... This practical guide is grounded in tested clinical practices and overall clinical applicability. It also addresses key aspects in the initiation maintenance and sustained growth of viable clinical programs in kidney and pancreas transplantation. more
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Methods of Cancer Diagnosis Th...Discussing the diagnosis therapy and prognosis in one self-contained text this... Discussing the diagnosis therapy and prognosis in one self-contained text this volume presents a broad view of the CNS tumor and brain tumor imaging fields of research in Europe. The genetics of malignant brain tumors and gene amplification are... more
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Advances in Experimental Medic...In his 1894 book Materials for the Study of Variation William Bateson coined t... In his 1894 book Materials for the Study of Variation William Bateson coined the term Homoeosis with the following prose: The case of the modification of the antenna of an insect into a foot of the eye of a Crustacean into an antenna of a petal into... more
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Advances in Experimental Medic...Numerous studies have pointed to the key role of complement in the pathogenesi... Numerous studies have pointed to the key role of complement in the pathogenesis of retinal disease particularly age-related macular degeneration (AMD). Reports about new gene associations and links to other physiological pathways are emerging almost... more
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Therapeutic Angiogenesis for V...Angiogenesis is the growth of new blood vessels and is a key process during pa... Angiogenesis is the growth of new blood vessels and is a key process during pathological disease progression. This book offers a definitive guide to the pathology of all the major angiogenic diseases and includes detailed descriptions of the latest... more
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Current Topics in Microbiology...From humble beginnings over 25 years ago as a lipid kinase activity associated... From humble beginnings over 25 years ago as a lipid kinase activity associated with certain oncoproteins PI3K (phosphoinositide 3-kinase) has been catapulted to the forefront of drug development in cancer immunity and thrombosis with the first... more
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Tumor Microenvironment: From M...Chronic inflammation is one of the major pathological bases manifesting the de... Chronic inflammation is one of the major pathological bases manifesting the development of gastric cancers hepatitis and hepatocellular carcinoma cervical cancer ulcerative colitis and colorectal cancer [1]. Microbial infections viral infections and... more
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Advances in Neurobiology: Cyto...This monograph begins with a general description of the cytoskeleton in axonal... This monograph begins with a general description of the cytoskeleton in axonal development and pathology and then moves to more detailed descriptions of particular components including microtubules and associated proteins neurofilaments and... more
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Clinical Gastroenterology: Chr...Covering all aspects of chronic liver failure in a single volume Chronic Liver... Covering all aspects of chronic liver failure in a single volume Chronic Liver Failure is designed to provide doctors with clinical answers for patients with liver diseases. Each chapter is written by a world renowned expert in their area and... more
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Minimally Invasive Surgery of ...Minimally Invasive Surgery of the Foot and Ankle represents a novel approach t... Minimally Invasive Surgery of the Foot and Ankle represents a novel approach to treatment of orthopedic problems in the foot and ankle. The gradual change of philosophy in the management of foot and ankle surgery means that patients require a less... more
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Anesthetic and Obstetric Manag...This book targets the entire markets of Anesthesiologists Obstetrician-Gynecol... This book targets the entire markets of Anesthesiologists Obstetrician-Gynecologists Fetologists and Nurse-Anesthesiologists. The text stands as the only authoritative guide to evaluate and manage the condition of both mother and child in a... more
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Biennial Review of Infertility...This volume brings together the most up-to-date information on male and female... This volume brings together the most up-to-date information on male and female infertility emerging assisted reproductive techniques and controversial issues in reproductive medicine. It highlights emerging controversies and contrasting points of view. more
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Encyclopedia of Traditional Ch...This set of six volumes provides a systematic and standardized description for... This set of six volumes provides a systematic and standardized description for 23 033 chemical components isolated from 6 734 medicinal plants. It provides a chemical structure with stereo-chemistry bonds for each chemical component. more
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Cancer Treatment and Research:...Progress in the treatment of cancer over the past two decades has been rapid w... Progress in the treatment of cancer over the past two decades has been rapid with many new and novel therapeutic modalities arriving at an unprecedented pace. Overall cancer mortality rates have actually begun to fall in parallel with progress in... more
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Decision Making in Radiation O...Decision Making in Radiation Oncology is a reference book designed to enable r... Decision Making in Radiation Oncology is a reference book designed to enable radiation oncologists including those in training to make diagnostic and treatment decisions effectively and efficiently. The design is based on the belief that a picture... more
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CT of the Acute Abdomen (Hardc...CT of the Acute Abdomen provides a comprehensive account of the use of CT in p... CT of the Acute Abdomen provides a comprehensive account of the use of CT in patients with acute abdomen. Recent important developments in CT including multislice CT and multiplanar reconstructions receive particular attention. CT features are... more
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Surgical Disorders of the Peri...Since the highly praised first edition of Surgical Disorders of the Peripheral... Since the highly praised first edition of Surgical Disorders of the Peripheral Nerves was published in 1998 greater understanding of the the molecular and cellular events which underlie the response of nerves to injury regeneration and neuropathic... more
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Current Topics in Microbiology...Hypoxia defined as reduced oxygen tension is a common physiological phenomenon... Hypoxia defined as reduced oxygen tension is a common physiological phenomenon in both normal embryonic development and malignancy progression. Although severe hypoxia is generally toxic for both normal tissue and tumors neoplastic cells gradually... more
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Decision Making in Radiation O...Decision Making in Radiation Oncology is a reference book designed to enable r... Decision Making in Radiation Oncology is a reference book designed to enable radiation oncologists including those in training to make diagnostic and treatment decisions effectively and efficiently. The design is based on the belief that a picture... more
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Milestones in Drug Therapy: Gl...Both metabotropic and ionotropic glutamate receptors present attractive drugga... Both metabotropic and ionotropic glutamate receptors present attractive druggable targets in treating disorders of the central nervous system. There has been a dramatic shift in the focus of glutamate-based therapies away from neurologic disorders... more
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Thoraco-Abdominal Aorta: Surgi...The thoraco-abdominal aortic pathology is not uncommon and represents the ulti... The thoraco-abdominal aortic pathology is not uncommon and represents the ultimate challenge for vascular surgeons. The book deals with the newest endovascular and hybrid approaches together with more traditional surgical strategies. Written by... more
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Molecular and Translational Me...Pharmacogenomic Testing in Current Clinical Practice: Implementation in the Cl... Pharmacogenomic Testing in Current Clinical Practice: Implementation in the Clinical Laboratory more
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Encyclopedia of Traditional Ch...This set of six volumes provides a systematic and standardized description of ... This set of six volumes provides a systematic and standardized description of 23 033 chemical components isolated from 6 926 medicinal plants collected from 5 535 books/articles published in Chinese and international journals. A chemical structure... more
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Side Effects of Drugs Annual S...The Side Effects of Drugs Annual was first published in 1977. It has been cont... The Side Effects of Drugs Annual was first published in 1977. It has been continually published since then as a yearly update to the voluminous encyclopedia Meyler s Side Effects of Drugs. Each new Annual continues to provide clinicians and medical... more
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Radiographic Atlas of Skeletal...This Atlas is principally based on the Brush Foundation Study of Human Growth ... This Atlas is principally based on the Brush Foundation Study of Human Growth and Development conceived in 1929 by Professor T. Wingate Todd of Western Reserve University School of Medicine. This intensive study collected data on the maturation of... more
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Cancer Treatment and Research:...Précis This book is a treatise about the origin of cancers. I would like to c... Précis This book is a treatise about the origin of cancers. I would like to convince readers that the basic tenets of the theory of a stem-cell origin of cancers also constitute a unified theory of cancer. Stem-cell origin of normal (and cancer)... more
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Health Assets in a Global Cont...As global health inequities continue to widen policymakers are redoubling thei... As global health inequities continue to widen policymakers are redoubling their efforts to address them. Yet the effectiveness and quality of these programs vary considerably sometimes resulting in the reverse of expected outcomes. While local... more
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Environmental Factors Genes an...Cancer is a complex disease. Only 5-10% of human cancers are hereditary in nat... Cancer is a complex disease. Only 5-10% of human cancers are hereditary in nature. Many of us think of environmental agents when we think of carcinogens. The environment includes all that surrounds us and environmental influences include not only... more
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New Liver Anatomy: Portal Segm...A new era for liver anatomy has dawned. With the development of multidetector ... A new era for liver anatomy has dawned. With the development of multidetector row computed tomography (MDCT) in the 1990s precise volume-rendered 3-D images could be constructed leading to new observations. Liver anatomy has since been reevaluated... more
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Veterinary Echocardiography 2e...Veterinary Echocardiography Second Edition is a fully revised version of the c... Veterinary Echocardiography Second Edition is a fully revised version of the classic reference for ultrasound of the heart covering two-dimensional M-mode and Doppler examinations for both small and large animal domestic species. Written by a... more
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Chiropractic Technique: Princi...**Selected for Doody s Core Titles(R) 2024 in Chiropractic** No other book off... **Selected for Doody s Core Titles(R) 2024 in Chiropractic** No other book offers a complete guide to chiropractic adjustive techniques! Chiropractic Technique 3rd Edition makes it easy to understand essential procedures and provides a rationale for... more
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Breast Cancer in the Post-Geno...Breast cancer is the most common tumor in women. It is the second leading caus... Breast cancer is the most common tumor in women. It is the second leading cause of cancer deaths worldwide. In this book international authorities offer a comprehensive approach to the biology diagnosis prevention and treatment of human breast... more
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Interventional Treatment of Ad...Advanced ischemic heart disease is fast becoming one of the most challenging p... Advanced ischemic heart disease is fast becoming one of the most challenging problems facing the modern cardiovascular physician and current established therapies often fail to adequately address this population of patients. As therapy of heart... more
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Rabbit Biotechnology: Rabbit G...Louis-Marie Houdebine and Jianglin Fan The study of biological functions of pr... Louis-Marie Houdebine and Jianglin Fan The study of biological functions of proteins and their possible roles in the pathogenesis of human diseases requires more and more relevant animal m- els. Although mice including genetically modified mice... more
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Human Papillomavirus: A Practi...This book is a practical and comprehensive guide to the diagnosis and treatmen... This book is a practical and comprehensive guide to the diagnosis and treatment of human papilloma virus (HPV)-related diseases from a urological perspective. It reviews new diagnostic methods for virus detection and typing management of penile and... more
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Burghardt s Colposcopy and Cer...A fourth edition of the world-famous text-atlas on colposcopy and cervical pat... A fourth edition of the world-famous text-atlas on colposcopy and cervical pathology Fully revised and updated Burghardt s landmark text on colposcopy and cervical pathology once again sets a new standard in the field. It offers specialists complete... more
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Springer Computational Neurosc...Increasing interest in the study of coordinated activity of brain cell ensembl... Increasing interest in the study of coordinated activity of brain cell ensembles reflects the current conceptualization of brain information processing and cognition. It is thought that cognitive processes involve not only serial stages of sensory... more
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MR Angiography of the Body: Te...Magnetic resonance angiography (MRA) continues to undergo exciting technologic... Magnetic resonance angiography (MRA) continues to undergo exciting technological advances that are rapidly being translated into clinical practice. It also has evident advantages over other imaging modalities including CT angiography and... more
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Neuroimmunology of the Skin: B...This important book provides a comprehensive and interdisciplinary review of t... This important book provides a comprehensive and interdisciplinary review of the molecular biology cell biology biochemistry and clinical aspects of nervous system-immune system interactions within the skin. It includes contributions from leading... more
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Dermatomyositis: Advances in R...Based on the vast personal experience of the authors this unique and clinical ... Based on the vast personal experience of the authors this unique and clinical guide provides the keys to interpreting the clinical symptoms of dermatomyositis. Also included are algorithms to help the reader to make the correct diagnosis. more
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Transanal Stapling Techniques ...It has never been easy to introduce new concepts and therapeutic in-tervention... It has never been easy to introduce new concepts and therapeutic in-terventions into surgical practice. When attempting to do so one is faced with the interagency of traditional dogma which still in this era of evidence-based medicine tends to... more
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Clinics in Developmental Medic...The only book to deal specifically with the treatment of gait problems in cere... The only book to deal specifically with the treatment of gait problems in cerebral palsy this comprehensive multi-disciplinary volume will be invaluable for all those working in the field of cerebral palsy and gait (neurologists therapists... more
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Applied Bioinformatics and Bio...Computational biology is an interdisciplinary research that applies approaches... Computational biology is an interdisciplinary research that applies approaches and methodologies of information sciences and engineering to address complex pr- lems in biology. With rapid developments in the omics and computer technologies over the... more
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Infectious Disease: Management...Recent evidence suggests an increasing rate of antimicrobial resistant pathoge... Recent evidence suggests an increasing rate of antimicrobial resistant pathogens throughout the world. Pathogens like Staphylococcus aureus are showing substantial prevalence of resistance to antibiotics. Thus we think that given these developments... more
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Advances in Experimental Medic...In this title the authors examine the Adenomatous polyposis cell (APC) gene wh... In this title the authors examine the Adenomatous polyposis cell (APC) gene which has emerged as the most commonly mutated gene in colorectal cancers. The aim of the book is to provide an overview of the diverse functions performed by the APC... more
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Hybrid PET/CT and SPECT/CT Ima...This practical guide is a reference source of cases for images obtained on sta... This practical guide is a reference source of cases for images obtained on state-of-the-art integrated PET/CT and SPECT/CT imaging systems. It covers the full spectrum of clinical applications including head and neck tumors breast cancer colorectal... more
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